Vlog 13: ALS Ice Bucket Challenge Hype | The Body of Evidence

Vlog 13: ALS Ice Bucket Challenge Hype


The media recently heralded the Ice Bucket Challenge a success following a breakthrough in ALS research: a new gene has been discovered!

Well... not quite. And the usual statements about "potential new treatments down the road" were one more layer of hype smeared onto a neat molecular discovery.

Let's dig into the original story (and learn about genes and proteins, whole exome sequencing, variants of unknown significance, penetrance, and more) and see how the media hyped this one up... again.


* Within Reason podcast discussing the Ice Bucket Challenge (starts at 53:43): http://withinreason.podbean.com/e/episode-203-jill-tarter-on-seti-funding/

* The Guardian report on the ALS "breakthrough": https://www.theguardian.com/society/2016/jul/26/ice-bucket-challenge-als...

* The American ALS Association's Press Release: http://www.alsa.org/news/media/press-releases/significant-gene-discovery...

* The Nature Genetics paper: http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3626.html

* The 2 papers that first identified NEK1 as a candidate gene for ALS: http://science.sciencemag.org/content/347/6229/1436  AND  http://brain.oxfordjournals.org/content/139/5/e28

* Health News Review's excellent take-down of the media hype: http://www.healthnewsreview.org/2016/07/ice-bucket-challenge-breakthroug...